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ea0084ps3-12-111 | Graves’ Disease 2 and Orbitopathy | ETA2022

Circulating marginal zone b cells and IGA serum levels as potential biomarkers of clinical activity of graves’ orbitopathy

Stojkovic Mirjana , Perovic Vladimir , Ciric Jasmina , Beleslin Biljana , Janic Tamara , Popadic Dusan , Zarkovic Milos

Objectives: The Clinical Activity Score (CAS) is used to measure and classify Graves orbitopathy activity (GO). However, CAS is partly subjective, and the evaluation of its components is binary. As CAS is known to be correlated with TSH receptor antibodies (TRAb), we wanted to evaluate other immunological parameters in the peripheral blood as markers of GO activity.Methods: The study included 32 patients (19 females, 13 males). CAS was evaluated by a sin...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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